1,4,5,6-Tetrahydropyrimidin-2-amine → HCID 178521194, compound

HRID 1391030Notes

Reaction equation

HRID 1391030 reaction equation
[NH2:1][C:2]1[NH:3][CH2:4][CH2:5][CH2:6][N:7]=1.[Cl:8][C:9]1[N:10]([CH2:15][C:16](OC)=[O:17])[C:11]([Cl:14])=[CH:12][CH:13]=1>>[Cl:8][C:9]1[N:10]([CH2:15][C:16]([N:1]=[C:2]2[NH:3][CH2:4][CH2:5][CH2:6][NH:7]2)=[O:17])[C:11]([Cl:14])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 32874121,4,5,6-Tetrahydropyrimidin-2-amineHCID 23453203HCID 23453203, compound

Product 1

HCID 178521194HCID 178521194, compound

Procedure

By a procedure analogous to Example 8, 2-amino-1,4,5,6-tetrahydropyrimidine is reacted with methyl (2,5-dichloro-1H-pyrrol-1-yl)acetate to give the title compound.

Sources & evidence

ORD record
ord-c291c6f8bc9b4d30a30675e26504f7f0
Source dataset
uspto-grants-1979_02
Patent number
US04140793

Reaction notes

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