Ethylene Glycol → Ethyl 8-(4-chlorophenylsulfonyl)-9-ethyl-1,4-dioxa-8-azaspiro[4.5]decane-7-carboxylate

HRID 139114Notes

Reaction equation

HRID 139114 reaction equation
[CH3:25][Si:26]([Cl:27])([CH3:28])[CH3:29].[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]2[CH:12]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[CH2:13][C:14](=[O:19])[CH2:15][CH:16]2[CH2:17][CH3:18])[cH:6][cH:7]1.[Cl:34][CH2:35][Cl:36].[OH:30][CH2:31][CH2:32][OH:33]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]2[CH:12]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[CH2:13][C:14]3([CH2:15][CH:16]2[CH2:17][CH3:18])[O:19][CH2:32][CH2:31][O:30]3)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 174Ethylene GlycolHCID 6344DichloromethaneHCID 6397ChlorotrimethylsilaneHCID 59342392Ethyl 1-(4-chlorophenylsulfonyl)-6-ethyl-4-oxopiperidine-2-carboxylate

Product 1

HCID 59342412Ethyl 8-(4-chlorophenylsulfonyl)-9-ethyl-1,4-dioxa-8-azaspiro[4.5]decane-7-carboxylate

Sources & evidence

ORD record
ord-7e9b2e749a9343d8b6f301ebdd8f6a44
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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