HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 3-(Acetylthio)butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | Crotonic Acid | HCID 637090 | — |
| Reactant | HCID 178418634 | HCID 178418634 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-(Acetylthio)butanoic acid | HCID 257707 | 92% |
Reaction Steps
40 ml of thioacetic acid are added to 43 g of crotonic acid in 100 ml of dioxane. After adding 20 mg of benzoyl peroxide, the mixture is kept at the boiling point under reflux for 6 hours. The solvent and the excess thioacetic acid are removed by distillation and the product is purified by vacuum distillation. 75 g (92% of theory) of 3-acetylmercapto-butyric acid are obtained; boiling point 94° to 95° C/0.45 mm Hg. nD20 1.4908.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04141734 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-b3ae3cfc5ec144bbb2b8b1ad3c9b775d |
| Source note | uspto-grants-1979_02 |