HCID 70608304, compound → HCID 86736364, compound

HRID 1391252Notes

Reaction equation

HRID 1391252 reaction equation
[CH3:1][N:2]1[CH2:8][CH2:7][CH2:6][C@:5]2([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([O:18]C)[CH:13]=3)[CH2:9][CH2:10][CH2:11][C@H:4]2[CH2:3]1.[ClH:20].CN1CCC[C@]2(C3C=CC=C(O)C=3)CCC[C@H]2C1>>[ClH:20].[CH3:1][N:2]1[CH2:8][CH2:7][CH2:6][C@:5]2([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([OH:18])[CH:13]=3)[CH2:9][CH2:10][CH2:11][C@@H:4]2[CH2:3]1

Participants

3

Reactant 2

HCID 70608304HCID 70608304, compoundHCID 70608796HCID 70608796, compound

Product 1

HCID 86736364HCID 86736364, compound

Procedure

By following the procedure set forth in Example 12, dl-trans-2-methyl-5a-(3-methoxyphenyl)-decahydrocyclopent[c]azepine was converted to dl-trans-2-methyl-5a-(3-hydroxyphenyl)-decahydrocyclopent[c]azepine hydrochloride. M.P. 160°-162° C.

Sources & evidence

ORD record
ord-2ac8d9f8f66447dc9d28505244f101b8
Source dataset
uspto-grants-1979_02
Patent number
US04141893

Reaction notes

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