HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Cyanide → (8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | 1-(Bromomethyl)-8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine | HCID 20205220 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | (8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl)acetonitrile | HCID 12562505 | — |
Reaction Steps
In the same manner 1-bromomethyl-8-chloro-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine can be condensed with potassium cyanide in dimethylsulfoxide to give 8-chloro-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04141902 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-5bbb2be3d8fd4f8e9b73b20ddf1cf316 |
| Source note | uspto-grants-1979_02 |