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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1391319Generated: November 3, 2026

M-Cresol → alpha-(3-Methylphenoxy)acetophenone

https://huagongshe.com/reaction/1391319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantM-CresolHCID 342—
ReactantWaterHCID 962—
ReactantPhenacyl bromideHCID 6259—
ReactantPotassium CarbonateHCID 11430—
SolventBenzeneHCID 241—
Productalpha-(3-Methylphenoxy)acetophenoneHCID 14970243—

Reaction Steps

Using an alternative condensation, equimolar amounts of m-cresol and alpha-bromoacetophenone are refluxed in benzene in the presence of potassium carbonate with azeotropic removal of water to provide alpha-(3-methylphenoxy)acetophenone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04141990
Source datasetuspto-grants-1979_02
ORD IDord-a5867a0ad753470595ffc7a8a1e10159
Source noteuspto-grants-1979_02