Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69199433, compound

HRID 1391396Notes

Reaction equation

HRID 1391396 reaction equation
[N:1]1([CH2:6][CH2:7][CH2:8][NH:9][C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:31].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:31].[ClH:31].[N:1]1([CH2:6][CH2:7][CH2:8][NH:9][C:10]2[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 12335258HCID 12335258, compound

Product 1

HCID 69199433HCID 69199433, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The N-(3-pyrrolidin-1-ylpropyl)-4-nitro-1-aminobenzene (13) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-1a4d61c33f8f4533af76a1d93330216b
Source dataset
uspto-grants-2008_03
Patent number
US07338536B2

Reaction notes

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