Acetophenone → (1-Phenylethylidene)hydrazine

HRID 1391409노트

반응식

HRID 1391409 반응식
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=O)[CH3:2].[NH2:10][NH2:11]>C(O)C>[C:1](=[N:10][NH2:11])([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 7410AcetophenoneHCID 9321Hydrazine

생성물 1

HCID 114650(1-Phenylethylidene)hydrazine수율 69%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

acetophenone (2.0 g, 16 mmol) is diluted in 16 ml of absolute ethanol and then hydrazine (2.3 ml, 48 mmol) is added. The mixture is heated to reflux temperature. After 2 h, the solvent is evaporated and the residue is taken up in ether (150 ml). The medium is washed with water (100 ml). After drying over Na2SO4, the ether is evaporated off. A pale yellow oil (1.5 g, 11 mmol, 69%) is obtained.

후처리

  1. temperatureThe mixture is heated
  2. temperatureto reflux temperature
  3. customthe solvent is evaporated
  4. washThe medium is washed with water (100 ml)
  5. dry with materialAfter drying over Na2SO4
  6. customthe ether is evaporated off

출처 및 근거

ORD 기록
ord-64bcc0fe4cae47a4881895edeae687f4
출처 데이터셋
uspto-grants-2008_03
특허 번호
US07338805B2

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