反应详情

acetophenone (2.0 g, 16 mmol) is diluted in 16 ml of absolute ethanol and then hydrazine (2.3 ml, 48 mmol) is added. The mixture is heated to reflux temperature. After 2 h, the solvent is evaporated and the residue is taken up in ether (150 ml). The medium is washed with water (100 ml). After drying over Na2SO4, the ether is evaporated off. A pale yellow oil (1.5 g, 11 mmol, 69%) is obtained.

1. temperatureThe mixture is heated
2. temperatureto reflux temperature
3. customthe solvent is evaporated
4. washThe medium is washed with water (100 ml)
5. dry with materialAfter drying over Na2SO4
6. customthe ether is evaporated off