Methyl iodide → HCID 783123, compound

Participants

Reaction Steps

A mixture of 1-Methyl-5-nitro-1,3-dihydro-benzoimidazole-2-thione (5.16 g, 24.7 mmol), Na2CO3 (2.88 g, 27.2 mmol) and MeI (3.68 g, 25.94 mmol) in acetone (150 ml) was refluxed overnight. The mix was filtered hot and the filtrate was concentrated to about 50 ml, the product was collected by filtration and washed with a small amount of cold CH2Cl2, drying left 4.58 g as a mustard yellow solid: LC/MS(m/e) at 224.0 [M+H]+, Rt at 1.55 min.

Provenance & Evidence