反应详情

温度

0 °C

4-(3-Nitro-benzenesulfonyl)-morpholine (5.9 g, 21.7 mmol) was combined with 10% palladium on carbon (1 g), ethanol (60 mL), and hydrazine (5 mL) and heated at reflux for 18 h. The solution was filtered through celite, concentrated, and cooled to 0° C. Product precipitated out an colorless crystal (4.7 g, 89%). MS (ESI) m/z=243 [M+H]+.

1. temperatureheated
2. temperatureat reflux for 18 h
3. filtrationThe solution was filtered through celite,
4. concentrationconcentrated
5. customProduct precipitated out an colorless crystal (4.7 g, 89%)