4-Amino-N-methylbenzeneethanesulfonamide → HCID 10196965, compound

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The title compound was prepared following the procedure of example two with N5-(2-chloro-pyrimidin-4-yl)-N2-(4-methoxy-benzyl)-1,N5-dimethyl-1H-benzoimidazole-2,5-diamine (82 mg, 0.20 mmol) and 2-(4-amino-phenyl)-ethanesulfonic acid methylamide (43 mg, 0.20 mmol) as a white solid (105 g, 85%). 1H NMR (300 MHz, d6-DMSO) δ 10.18 (br s, 1H), 9.46 (br s, 1H), 7.88 (d, J=6.6 Hz, 1H), 7.54-7.62 (m, 3H), 7.40-7.47 (M, 3H), 7.18-7.26 (M, 3H), 7.01 (M, 1H), 6.92 (d, J=8.4 Hz, 2H), 5.83 (d, J=6.3 Hz, 1H), 4.68 (d, J=5.4 Hz, 2H), 3.73 (s, 3H), 3.72 (s, 3H), 3.48 (s, 3H), 3.23-3.28 (m, 2H), 2.87-2.93 (M, 2H), 2.60 (d, J=4.8 Hz, 3H). MS (ESI) m/z=587 [M+H]+.

Provenance & Evidence