4-[(methylsulfonyl)methyl]aniline(SALTDATA: FREE) → HCID 10196841, compound

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The title compound was prepared following the procedure of example one with N2-(4-Chloro-benzyl)-N5-(2-chloro-pyrimidin-4-yl)-1,N5-dimethyl-1H-benzoimidazole-2,5-diamine (103 mg, 0.25 mmol) and 4-[(methylsulfonyl)methyl]aniline (46 mg, 0.25 mmol) as a white solid (61 mg, 41%). 1H NMR (300 MHz, d6-DMSO+NaHCO3) δ 9.20 (s, 1H), 7.76-7.80 (m, 3H), 7.36-7.43 (m, 5H), 7.24 (d, J=8.1 Hz, 2H), 7.08 (d, J=1.8 Hz, 1H), 6.85 (dd, J=8.1 and 1.8 Hz, 1H), 5.63 (d, J=6.0 Hz, 1H), 4.58 (d, J=5.7 Hz, 2H), 4.34 (s, 2H), 3.58 (s, 3H), 3.43 (s, 3H), 2.85 (s, 3H). MS (ESI) m/z=562 [M+H]+.

Provenance & Evidence