Methanol → 4'-Hydroxy-3'-iodo-3-methyl-1,1'-biphenyl-4-carbonitrile

HRID 139158Notes

Reaction equation

HRID 139158 reaction equation
[CH3:21][OH:22].[I-:17].[Na+:18].[Na+:20].[OH-:19].[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH3:16])[c:11]([C:14]#[N:15])[cH:12][cH:13]2)[cH:6][cH:7]1>>[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH3:16])[c:11]([C:14]#[N:15])[cH:12][cH:13]2)[cH:6][c:7]1[I:17]

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 30165Iodide IonHCID 136359914'-Hydroxy-3-methyl-1,1'-biphenyl-4-carbonitrile

Product 1

HCID 222746294'-Hydroxy-3'-iodo-3-methyl-1,1'-biphenyl-4-carbonitrile

Sources & evidence

ORD record
ord-e05934cd0e9e4534845d6775fdf6da62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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