HCID 21417378, compound → HCID 10240070, compound

Participants

Reaction Steps

The title compound was prepared following the procedure of example one with N2-(4-Chloro-benzyl)-N5-(2-chloro-pyrimidin-4-yl)-1,N5-dimethyl-1H-benzoimidazole-2,5-diamine (103 mg, 0.25 mmol) and methanesulfonic acid 3-amino-phenyl ester (56 mg, 0.25 mmol) as a white solid (87 mg, 58%). 1H NMR (300 MHz, d6-DMSO+NaHCO3) δ 9.40 (s, 1H), 8.00 (s, 1H), 7.79 (d, J=6.0 Hz, 1H), 7.64 (d, J=8.1 Hz, 1H), 7.50 (t, J=5.7 Hz, 1H), 7.36-7.44 (m, 4H), 7.23-7.29 (m, 2H), 7.08 (s, 1H), 6.84 (d, J=8.1 Hz, 2H), 5.65 (d, J=5.7 Hz, 1H), 4.58 (d, J=5.7 Hz, 2H), 3.58 (s, 3H), 3.43 (s, 3H), 3.34 (s, 3H). MS (ESI) m/z=564 [M+H]+.

Provenance & Evidence