Benzenesulfonamide, 3-amino- → HCID 69265373, compound

Participants

Reaction Steps

The title compound was prepared following the procedure of example 1 with N5-(2-chloropyrimidin-4-yl)-N2-isopropyl-N5,1-dimethyl-1H-benzimidazole-2,5-diamine (83 mg, 0.25 mmol) and 3-amino-benzenesulfonamide (43 mg, 0.25 mmol) as a white solid (59 mg, 47%). 1H NMR (300 MHz, d6-DMSO) δ 11.03 (s, 1H), 8.94 (d, J=8.1 Hz, 1H), 8.35 (s, 1H), 7.97 (d, J=7.2 Hz, 1H), 7.71 (d, J=7.2 Hz, 1H), 7.66 (d, J=8.4 Hz, 1H), 7.48-7.57 (m, 3H), 7.40 (s, 1H), 7.33 (dd, J=8.4 and 1.5 Hz, 1H), 5.90 (s, 1H), 4.12 (m, 1H), 3.70 (s, 3H), 3.54 (s, 3H), 1.33 (d, J=6.3 Hz, 6H) ppm. MS (ESI) m/z=467 [M+H]+.

Provenance & Evidence