4-[(methylsulfonyl)methyl]aniline(SALTDATA: FREE) → HCID 10239519, compound

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Reaction Steps

The title compound was prepared following the procedure of example 1 with N2-tert-butyl-N5-(2-chloro-pyrimidin-4-yl)-1,N5-dimethyl-1H-benzoimidazole-2,5-diamine (69 mg, 0.20 mmol) and 4-[(methylsulfonyl)methyl]aniline (37 mg, 0.20 mmol) as a white solid (111 mg, 95%). 1H NMR (300 MHz, d6-DMSO) δ 9.28 (s, 1H), 7.77-7.79 (m, 3H), 7.24 (d, J=8.4 Hz, 3H), 7.16 (d, J=1.5 Hz, 1H), 6.88 (d, J=7.8 Hz, 1H), 6.21 (br s, 1H), 5.67 (d, J=6.0 Hz, 1H), 4.35 (s, 2H), 3.54 (s, 3H), 3.45 (s, 3H), 2.86 (s, 3H), 1.47 (s, 9H) ppm. MS (ESI) m/z=494 [M+H]+.

Provenance & Evidence