3-methyl-N-(1-methylethyl)-2-nitrobenzamide → 2-amino-3-methyl-N-(1-methylethyl)benzamide

Participants

Reaction Steps

The 2-nitrobenzamide of Step A (1.70 g, 7.6 mmol) was hydrogenated over 5% Pd/C in 40 mL of ethanol at 50 psi. When the uptake of hydrogen ceased the reaction was filtered through celite and the celite was washed with ether. The filtrate was evaporated under reduced pressure to afford 1.41 g of the title compound as a solid melting at 149-151° C.

Provenance & Evidence