HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-chlorobenzoic acid → HCID 178433409, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-chlorobenzoic acid | HCID 12476 | — |
| Reactant | Acetamidine monohydrochloride | HCID 67170 | — |
| Solvent | Glycol monoethyl ether | HCID 8076 | — |
| Product | HCID 178433409 | HCID 178433409 | 38.6% |
Reaction Steps
2-Amino-5-chlorobenzoic acid (3.58 g, 20.9 mmol, 1 eq.), acetamidine hydrochloride (2.36 g, 25.1 mmol, 1.2 eq.) and 2-ethoxyethanol (70 mL) were mixed and refluxed for 48 h. The resultant solids were filtered and dried to yield 1.57 g of yellow solid product. MS (ES+)=195/197 (M+H)++.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07338947B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-8b165043bece4ac4ab78cb842a1ef465 |
| Source note | uspto-grants-2008_03 |