反应详情

温度

130 °C

Compound 1 (500 mg, 1.44 mmol) and hydrazine (4 ml) were put in a pressure tube. Ethanol (30 ml) was added. The pressure tube was flushed with argon, sealed and stirred at 100-160° C. for 10-16 h. After cooling, the resulting solid was collected and washed with methanol and ether to give compound 138 (40 mg). The product was used in the next step without further purification.

1. customThe pressure tube was flushed with argon
2. customsealed
3. temperatureAfter cooling
4. customthe resulting solid was collected
5. washwashed with methanol and ether