Toluene → HCID 69214809, compound

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Reaction Steps

A mixture of 6-[4-(2-formylphenyl)benzyl]-8-(3,5-dichloro-phenyl)-1,8-diazabicyclo[4.3.0]nonane-7,9-dione (0.205 g) and methyl (triphenylphosphoranylidene)acetate (0.223 g) in toluene (5 mL) was refluxed for 8 hours. The mixture was evaporated and the residue was purified by chromatography (Silica gel: EtOAc/hexane: 1/4 to 1/3, Chromatotron) to afford the titled compound (0.229 g). MS (m/z) 571(M++Na).

Provenance & Evidence