Dimethyl Sulfoxide → [2-Methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetonitrile
Reaction equation
[CH3:24][S:25](=[O:26])[CH3:27].[Cl:1][CH2:2][c:3]1[c:4]([CH3:19])[n:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[cH:7][cH:8]1.[Na:20][C:21]#[N:22].[OH2:23]>>[CH2:2]([c:3]1[c:4]([CH3:19])[n:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[cH:7][cH:8]1)[C:21]#[N:22]Participants
5
Sources & evidence
- ORD record
- ord-54d92d1bb14d46d7aa56756300c029ee
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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