HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 20786265, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 4-Pyridineethanol | HCID 72921 | — |
| Reactant | Diethyl azodicarboxylate | HCID 5462977 | — |
| Reactant | HCID 22479133 | HCID 22479133 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20786265 | HCID 20786265 | — |
Reaction Steps
To a mixture of the compound from Example 196 (0.15 g), Ph3P (0.22 g) and 4-hydroxyethylpyridine ((0.070 mL) in anhydrous CH2Cl2 (3 mL) was added DEAD (0.15 mL) under N2. After 30 minutes the reaction mixture was concentrated and the residue was purified via HPLC to give the desired compound (97 mg). MS m/z 498(MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07342012B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-709b4e6351914d588bdc3be1493bc2fd |
| Source note | uspto-grants-2008_03 |