14008-79-8 → HCID 131726803, compound

HRID 1392355Notes

Reaction equation

HRID 1392355 reaction equation
[CH3:1][C:2]1[O:8][C:7]([C:9]([NH:11][CH2:12][C:13]2[CH:18]=[CH:17][C:16]([C:19]3[CH:24]=[CH:23][C:22]([C:25]#[N:26])=[CH:21][CH:20]=3)=[CH:15][CH:14]=2)=[O:10])=[C:6]([OH:27])[C:4](=[O:5])[CH:3]=1.[CH3:28][N:29]1[CH:33]2[CH2:34][CH:35]([O:37][CH:38]([C:45]3[CH:50]=[CH:49][C:48]([Cl:51])=[CH:47][CH:46]=3)[C:39]3[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=3)[CH2:36][CH:30]1[CH2:31][CH2:32]2.[ClH:52]>>[CH3:28][N:29]1[CH:33]2[CH2:34][CH:35]([O:37][CH:38]([C:45]3[CH:50]=[CH:49][C:48]([Cl:51])=[CH:47][CH:46]=3)[C:39]3[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=3)[CH2:36][CH:30]1[CH2:31][CH2:32]2.[ClH:52].[CH3:1][C:2]1[O:8][C:7]([C:9]([NH:11][CH2:12][C:13]2[CH:18]=[CH:17][C:16]([C:19]3[CH:20]=[CH:21][C:22]([C:25]#[N:26])=[CH:23][CH:24]=3)=[CH:15][CH:14]=2)=[O:10])=[C:6]([OH:27])[C:4](=[O:5])[CH:3]=1

Participants

3

Reactant 2

HCID 20313514008-79-8HCID 54681831HCID 54681831, compound

Product 1

HCID 131726803HCID 131726803, compound

Procedure

To a 100-mL round-bottom flask, equipped with a magnetic stirbar, was charged 9.92 g (165 mmol) of AM-5. Next, 20 g (16.5 mmol) of FC-1 was added to the flask at room temperature over about 1 hour. After stirring for one additional hour, volatiles were removed at temperatures up to 130° C. at 2.5 mm pressure to provide FC-1/AM-5, nominal molecular weight=1239.1 g/mol.

Workup

  1. customTo a 100-mL round-bottom flask, equipped with a magnetic stirbar
  2. customwere removed at temperatures up to 130° C. at 2.5 mm pressure

Sources & evidence

ORD record
ord-f8323ad849bc45fb825e64ee795c9157
Source dataset
uspto-grants-2008_03
Patent number
US07342080B2

Reaction notes

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