HuagongsheHuagongshe Chemistry Print Report · For research reference only
6,8-Difluoro-2-tetralone → 3-{4-[2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoylamino]-imidazol-1-yl}-butyric acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6,8-Difluoro-2-tetralone | HCID 4076431 | — |
| Reactant | 3-[4-(2-Amino-pentanoylamino)-imidazol-1-yl]-butyric acid methyl ester | HCID 67165548 | — |
| Product | 3-{4-[2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoylamino]-imidazol-1-yl}-butyric acid methyl ester | HCID 11655289 | — |
Reaction Steps
3-[4-(2-Amino-pentanoylamino)-imidazol-1-yl]-butyric acid methyl ester was reacted with 6,8-Difluoro-3,4-dihydro-1H-naphthalen-2-one to provide the title compound: MS m/z 449.3 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07342118B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-5c8d78a848d44dcfb1e051bb14a5bacf |
| Source note | uspto-grants-2008_03 |