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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1392521Generated: October 31, 2026

2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide → HCID 11627479, compound

https://huagongshe.com/reaction/1392521

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amideHCID 67164226—
ReactantHCID 67165381HCID 67165381—
ProductHCID 11627479HCID 11627479—

Reaction Steps

2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide was reacted with 6,8-Difluoro-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one to afford the title compound: C13 NMR (100 MHz, CDCl3) 14.3, 19.4, 19.7, 22.5, 23.0, 24.3, 24.8, 26.3, 26.6, 27.4, 27.5, 29.7, 36.4, 37.1, 38.0, 45.8, 47.6, 56.0, 59.2, 60.7, 62.5, 63.0, 65.5, 67.3, 104.7, 104.8, 111.0, 110.2, 112.5, 131.1, 131.2, 137.2, 172.2; MS m/z 502.3. (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07342118B2
Source datasetuspto-grants-2008_03
ORD IDord-8bdb1b4a915041b3978898744a5bc278
Source noteuspto-grants-2008_03