HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid → HCID 11656313, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid | HCID 21112802 | — |
| Reactant | HCID 67165250 | HCID 67165250 | — |
| Product | HCID 11656313 | HCID 11656313 | — |
Reaction Steps
Following the procedure for Example 86, 2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid (diastereomer 2) was reacted with 1-[1,1-Dimethyl-2-(4-methyl-piperazin-1-yl)-ethyl]-1H-imidazol-4-ylamine to afford the title compound: C13 NMR (100 MHz, CDCl3) 14.2, 19.5, 25.8, 25.9, 28.2, 28.9, 29.7, 36.5, 46.1, 52.9, 55.0, 55.7, 59.0, 60.9, 68.2, 101.1, 101.3, 104.5, 110.9, 131.3, 137.3, 172.3; MS m/z 503.3 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07342118B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-d74c052fef5b4ed181cd26976f8372cf |
| Source note | uspto-grants-2008_03 |