反应详情

p-Chloroaniline (3.82 g) was dissolved in ethyl acetate (30 ml), and chloroacetyl chloride (2.39 ml) was added at room temperature to stir the mixture for 1 hour. After the reaction mixture was heated and stirred at 60° C. for 3.5 hours, crystals deposited were collected by filtration to obtain the title compound (4.78 g). The filtrate was concentrated to about ¼, and crystals deposited were collected by filtration to obtain the title compound (1.01 g).

1. temperatureAfter the reaction mixture was heated
2. stirringstirred at 60° C. for 3.5 hours
3. filtrationcrystals deposited were collected by filtration