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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1392996Generated: October 25, 2026

Calcium Sulfate Dihydrate → Ibuprofen, (+-)-

https://huagongshe.com/reaction/1392996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCalcium Sulfate DihydrateHCID 24928—
ReactantIbuprofen, Sodium SaltHCID 5338317—
ReactantGentamicin SulfateHCID 9855350—
ProductIbuprofen, (+-)-HCID 3672—

Reaction Steps

A mixture of 1,000.0 mg calcium sulfate dihydrate (Fluka), 250.0 mg poly-L-lactide (M-10,000 g/mol), 49.7 mg gentamicin sulfate (AK 628) and 78.5 mg ibuprofen sodium salt (produced through the neutralization of ibuprofen (Fluka)) is ground up. 200 mg of this mixture, respectively, are pressed with a press at a pressure of 5 tons within a period of two minutes into disk-shaped molded bodies with a diameter of 13 mm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07345024B2
Source datasetuspto-grants-2008_03
ORD IDord-3d66397312594603a9d6836f64207d8f
Source noteuspto-grants-2008_03