Acetyl chloride → HCID 67422775, compound

HRID 1393023Notes

Reaction equation

HRID 1393023 reaction equation
[CH3:1][NH:2][CH:3]1[CH2:16][C:15]2[C:6]([CH3:25])([CH:7]3[CH:12]([CH2:13][CH:14]=2)[CH:11]2[CH2:17][CH2:18][CH:19]4[CH:20]([CH3:24])[N:21]([CH3:23])[CH2:22][C:10]24[CH2:9][CH2:8]3)[CH2:5][CH2:4]1.[S:26]1[CH:30]=[CH:29][CH:28]=[C:27]1[CH2:31][C:32](Cl)=[O:33].C(Cl)(=O)C>>[CH3:1][N:2]([CH:3]1[CH2:16][CH:15]2[C:6]([CH3:25])([CH:7]3[CH:12]([CH2:13][CH2:14]2)[CH:11]2[CH2:17][CH2:18][CH:19]4[CH:20]([CH3:24])[N:21]([CH3:23])[CH2:22][C:10]24[CH2:9][CH2:8]3)[CH2:5][CH2:4]1)[C:32](=[O:33])[CH2:31][C:27]1[S:26][CH:30]=[CH:29][CH:28]=1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 1623622-Thiopheneacetyl chlorideHCID 551434Kurchine

Product 1

HCID 67422775HCID 67422775, compound

Procedure

The title compound was prepared according to procedures described in Example 7C, except substituting Compound 172B for Compound 7B and 2-thiopheneacetyl chloride for acetyl chloride. 1H NMR (CDCl3): δ 0.74 (s, 3 H) 0.95-2.40 (m, 27 H) 2.83 (s, 3 H) 2.88 (s, 3 H) 3.01 (m, 1 H) 3.69 (m, 1 H) 3.90 (d, J=11.53 Hz, 2 H) 4.49 (m, 1 H) 6.92 (m, 2 H) 7.19 (m, 1 H); (M+H)+=469.

Sources & evidence

ORD record
ord-cde79aaae8e946069be333e95d6cf9d4
Source dataset
uspto-grants-2008_03
Patent number
US07345034B2

Reaction notes

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