反应详情

To a strred solution of N-(2-hydroxy-phenyl)-benzamide (0.81 g, 3.80 mmol), and cesium carbonate (1.61 g, 4.94 mmol) in acetonitrile was added epibromohydrin (0.63 ml, 7.60 mmol). After 4 hours the reaction mixture was partitioned between dichloromethane and water. After evaporation of the organic solvent, the residue was crystallized from petroleum ether and diethyl ether yielding the title compound (0.741 g, 73%).

1. customAfter 4 hours the reaction mixture was partitioned between dichloromethane and water
2. customAfter evaporation of the organic solvent
3. customthe residue was crystallized from petroleum ether and diethyl ether yielding the title compound (0.741 g, 73%)