N-(2-Oxiranylmethoxy-phenyl)-benzamide → HCID 9934301, compound

HRID 1393054Notes

Reaction equation

HRID 1393054 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][CH:9]2[CH2:13][CH2:12][NH:11][CH2:10]2)=[N:6][CH:7]=1.[O:14]1[CH2:16][CH:15]1[CH2:17][O:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[NH:25][C:26](=[O:33])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][CH:9]2[CH2:13][CH2:12][N:11]([CH2:16][CH:15]([OH:14])[CH2:17][O:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=3[NH:25][C:26](=[O:33])[C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[CH2:10]2)=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 22386962N-(2-Oxiranylmethoxy-phenyl)-benzamideHCID 62349642HCID 62349642, compound

Product 1

HCID 9934301HCID 9934301, compound

Procedure

A solution of 5-chloro-2-(3-pyrrolidinyloxy) pyridine (100 μL, 0.2M/DMSO), N-[2-(2-oxiranylmethoxy)phenyl]benzamide (100 μL, 0.2 M/DMSO) was refluxed for 3 h.

Sources & evidence

ORD record
ord-7985cc8d9e83422a9fbbae6fde2bde50
Source dataset
uspto-grants-2008_03
Patent number
US07345063B2

Reaction notes

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