9-(4-Chlorophenylsulfonyl)-2-(hydroxymethylene)-9-azabicyclo[3.3.1]nonan-3-one → 16-(4-Chloro-benzenesulfonyl)-7-methylthio-4,6,8,9,16-pentaaza-tetracyclo-[10,3,1,02,10,05,9]hexadeca-2(10),3,5,7-tetraene

HRID 1393250Notes

Reaction equation

HRID 1393250 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]2[CH:16]3[CH2:17][CH2:18][CH2:19][CH:12]2[C:13](=[CH:21]O)[C:14](=O)[CH2:15]3)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH2:23][C:24]1[N:28]=[C:27]([S:29][CH3:30])[NH:26][N:25]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]2[CH:16]3[CH2:17][CH2:18][CH2:19][CH:12]2[C:13]2[CH:21]=[N:23][C:24]4[N:25]([C:14]=2[CH2:15]3)[N:26]=[C:27]([S:29][CH3:30])[N:28]=4)(=[O:10])=[O:9])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 668419749-(4-Chlorophenylsulfonyl)-2-(hydroxymethylene)-9-azabicyclo[3.3.1]nonan-3-oneHCID 178503514HCID 178503514, compound

Product 1

HCID 6845447116-(4-Chloro-benzenesulfonyl)-7-methylthio-4,6,8,9,16-pentaaza-tetracyclo-[10,3,1,02,10,05,9]hexadeca-2(10),3,5,7-tetraene

Procedure

Prepared as described in Example 5 using 9-(4-chlorophenylsulfonyl)-2-(hydroxymethylene)-9-azabicyclo[3.3.1]nonan-3-one which was prepared as described in Example 34 and 3-amino-5-methylthio-1,2,4-triazole.

Workup

  1. customPrepared
  2. customwas prepared

Sources & evidence

ORD record
ord-a686ad2e5efb486ebd136e6878c5b3ec
Source dataset
uspto-grants-2008_03
Patent number
US07345056B2

Reaction notes

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