Methylhydrazine → HCID 178481711, compound

HRID 1393255Notes

Reaction equation

HRID 1393255 reaction equation
[CH3:1][NH:2][NH2:3].[Cl:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]2[CH:19]3[CH2:20][CH2:21][CH2:22][CH:15]2[CH:16]([C:24]([O:26]C)=O)[C:17](=O)[CH2:18]3)(=[O:13])=[O:12])=[CH:7][CH:6]=1.C(=O)(OC)OC.ClC1C=CC(S(N2C3CCCC2CC(=O)C3)(=O)=O)=CC=1>>[Cl:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]2[CH:19]3[CH2:20][CH2:21][CH2:22][CH:15]2[C:16]2[C:17]([CH2:18]3)=[N:3][N:2]([CH3:1])[C:24]=2[OH:26])(=[O:13])=[O:12])=[CH:7][CH:6]=1

Participants

5

Reactant 4

HCID 6061MethylhydrazineHCID 12021Dimethyl CarbonateHCID 161174379-(4-Chlorobenzene-1-sulfonyl)-9-azabicyclo[3.3.1]nonan-3-oneHCID 66842588HCID 66842588, compound

Product 1

HCID 178481711HCID 178481711, compound

Procedure

Prepared as described in Example using methylhydrazine and methyl 9-(4-chlorophenylsulfonyl)-3-oxo-9-azabicyclo[3.3.1]nonane-2-carboxylate, which was prepared as described in Example 12 using dimethyl carbonate and 9-(4-chlorophenylsulfonyl)-9-azabicyclo[3.3.1]nonan-3-one. See also: Bonjoch, Josep; Linares, Ana; Guardia, Manel; Bosch, Joan. Heterocycles 1987, 26(8), 2165-74.

Workup

  1. customPrepared
  2. customwas prepared

Sources & evidence

ORD record
ord-ff617f7553004a0595707df01809a863
Source dataset
uspto-grants-2008_03
Patent number
US07345056B2

Reaction notes

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