1-Indanone, 4-bromo- → 4-(4-Bromo-indan-1-ylmethyl)-1,3-dihydro-imidazole-2-thione

HRID 1393298Notes

Reaction equation

HRID 1393298 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][C:6]2=O.BrC1C=CC=C2C=1C[CH:16]([C:22]1[NH:23][C:24](=[S:27])[NH:25][CH:26]=1)C2>>[Br:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][CH:6]2[CH2:16][C:22]1[NH:23][C:24](=[S:27])[NH:25][CH:26]=1

Participants

3

Reactant 2

HCID 987131-Indanone, 4-bromo-HCID 219861684-(4-Bromo-indan-2-yl)-1,3-dihydroimidazole-2-thione

Product 1

HCID 219860654-(4-Bromo-indan-1-ylmethyl)-1,3-dihydro-imidazole-2-thione

Procedure

Use of 4-bromoindanone (Obtained by the Procedures in Example NINETEEN-1 (Compound 149) in Method TWENTYFOUR Produced 4-(4-bromo-indan-1-ylmethyl)-1,3-dihydro-imidazole-2-thione (Compound 167)

Sources & evidence

ORD record
ord-3328093b71d74694a70c48f289a33b26
Source dataset
uspto-grants-2008_03
Patent number
US07345077B2

Reaction notes

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