Aluminium lithium hydride → HCID 15676492, compound

HRID 1393353Notes

Reaction equation

HRID 1393353 reaction equation
[C:1]1([C:7]2[S:8][C:9]3[C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=[CH:12][C:10]=3[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[C:1]1([C:7]2[S:8][C:9]3[C:15]([CH2:16][OH:17])=[CH:14][CH:13]=[CH:12][C:10]=3[N:11]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 23033929HCID 23033929, compound

Product 1

HCID 15676492HCID 15676492, compoundYield 94%

Procedure

Ethyl ester of 2-phenylbenzothiazole-7-carboxylic acid (425 mg, 1.50 mmol) was reduced by using lithium aluminium hydride as in Preparation 2-3) to give 2-phenylbenzothiazole-7-methanol (340 mg, 94%) as colorless crystals.

Workup

  1. customas in Preparation 2-3)

Sources & evidence

ORD record
ord-d41e14f3a4ec45a7a37f92f34bb13dba
Source dataset
uspto-grants-2008_03
Patent number
US07345068B2

Reaction notes

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