Dimethylamine → HCID 23033921, compound

HRID 1393359Notes

Reaction equation

Br[CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[C:7]([C:14](O)=[O:15])[CH:8]=[CH:9][CH:10]=2)[O:5][C:4]=1[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[CH3:23][NH:24][CH3:25]>>[CH3:23][N:24]([CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[C:7]([CH2:14][OH:15])[CH:8]=[CH:9][CH:10]=2)[O:5][C:4]=1[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH3:25]

Participants

Reactant 2

HCID 674Dimethylamine

HCID 23033917HCID 23033917, compound

Product 1

HCID 23033921HCID 23033921, compound

Procedure

Ethyl ester of 3-bromomethylflavone-8-carboxylic acid was reacted with dimethylamine in a conventional manner and the resultant product was reduced to give 3-dimethylaminomethylflavone-8-methanol.

Sources & evidence

ORD record: ord-555328b6b5c040eea5896524e62f4cd3
Source dataset: uspto-grants-2008_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07345068B2

Reaction notes

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