HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Methyl-2-thiophen-2-yloxazol-4-yl)ethyl tosylate → 2-(3,4-Difluoro-phenoxy)-2-methyl-3-(4-[2-(5-methyl-2-thiophen-2-yl-oxazol-4-yl)-ethoxy]-phenyl}-propionic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Methyl-2-thiophen-2-yloxazol-4-yl)ethyl tosylate | HCID 22340042 | — |
| Reactant | 2-(3,4-Difluorophenoxy)-3-(4-hydroxyphenyl)-2-methyl-propionic acid ethyl ester | HCID 69319839 | — |
| Product | 2-(3,4-Difluoro-phenoxy)-2-methyl-3-(4-[2-(5-methyl-2-thiophen-2-yl-oxazol-4-yl)-ethoxy]-phenyl}-propionic Acid | HCID 22340002 | — |
Reaction Steps
The title compound was prepared from 2-(3,4-difluoro-phenoxy)-3-(4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester and toluene-4-sulfonic acid 2-(5-methyl-2-thiophen-2-yl-oxazol-4-yl)-ethyl ester using the method of Example 56.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07345070B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-617c7fdd0ca8469ab99b34bb2337fc87 |
| Source note | uspto-grants-2008_03 |