2-(5-Methyl-2-phenyloxazol-4-yl)ethyl 4-methylbenzenesulfonate → HCID 69316509, compound
Reaction equation
C([O:3][C:4](=[O:26])[C:5]([O:15][C:16]1[CH:21]=[CH:20][C:19]([S:22]([CH3:25])(=[O:24])=[O:23])=[CH:18][CH:17]=1)([CH3:14])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)C.[C:27]1([C:33]2[O:34][C:35]([CH3:51])=[C:36]([CH2:38][CH2:39]OS(C3C=CC(C)=CC=3)(=O)=O)[N:37]=2)[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH3:25][S:22]([C:19]1[CH:18]=[CH:17][C:16]([O:15][C@@:5]([CH3:14])([CH2:6][C:7]2[CH:12]=[CH:11][C:10]([O:13][CH2:39][CH2:38][C:36]3[N:37]=[C:33]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=4)[O:34][C:35]=3[CH3:51])=[CH:9][CH:8]=2)[C:4]([OH:3])=[O:26])=[CH:21][CH:20]=1)(=[O:24])=[O:23]Participants
3
Procedure
Standard Procedure (B) was utilized to prepare the title compound from 3-(4-hydroxyphenyl)-2-(4-methanesulfonyl-phenoxy)-2-methyl-propionic acid ethyl ester and toluene-4-sulfonic acid 2-(2-phenyl-5-methyl-oxazol-4-yl)-ethyl ester.
Sources & evidence
- ORD record
- ord-cbcc2539aa5a4d709fa0ed6dae21ee40
- Source dataset
- uspto-grants-2008_03
- Patent number
- US07345070B2
Reaction notes
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