4-Chlorobenzenesulfonyl chloride → HCID 10282321, compound

HRID 1393593Notes

Reaction equation

HRID 1393593 reaction equation
[CH3:1][O:2][C:3](=[O:32])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[C:9]([NH2:31])=[CH:10][C:11]2[N:15]=[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[N:13]([C:22]3[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=3)[C:12]=2[CH:30]=1.[Cl:33][C:34]1[CH:39]=[CH:38][C:37]([S:40](Cl)(=[O:42])=[O:41])=[CH:36][CH:35]=1>>[CH3:1][O:2][C:3](=[O:32])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[C:9]([NH:31][S:40]([C:37]2[CH:38]=[CH:39][C:34]([Cl:33])=[CH:35][CH:36]=2)(=[O:42])=[O:41])=[CH:10][C:11]2[N:15]=[C:14]([C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)[N:13]([C:22]3[CH:23]=[CH:24][C:25]([O:28][CH3:29])=[CH:26][CH:27]=3)[C:12]=2[CH:30]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 67364953HCID 67364953, compound

Product 1

HCID 10282321HCID 10282321, compound

Procedure

4-[(5-Amino-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl)oxy]butanoic acid methyl ester was reacted with 4-chlorobenzenesulfonic acid chloride according to general operating instructions 13.

Sources & evidence

ORD record
ord-2db3546ec01f495eabb4e0e25546b54c
Source dataset
uspto-grants-2008_03
Patent number
US07345075B2

Reaction notes

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