Hydrochloric Acid → HCID 23091902, compound

Participants

Reaction Conditions

Reaction Steps

4-Amino-3-mercapto-5-methoxybenzoic acid (600 mg) and thiobenzamide (450 mg) were suspended in ethylene glycol (10 ml). Conc. hydrochloric acid (1.0 ml) was added thereto, and the mixture was stirred for 7 hours at 60° C. The reaction mixture was cooled to room temperature, then cold water was added thereto, and precipitated crystals were collected by filtration and washed with water and n-hexane. The crystals were dried under reduced pressure to give the title compound (280 mg, Y.:32%) as white crystals.

Provenance & Evidence