反应详情

温度

130 °C

4-Amino-3-hydroxybenzoic acid (4.9 g) was added to acetic acid (250 ml) and stirred for 3 days at 130° C. The solution was concentrated under reduced pressure, and precipitates were collected by filtration. The precipitates were dissolved in methanol and chloroform. The solution was concentrated under reduced pressure, and precipitates were collected by filtration, washed with methanol and dried under reduced pressure to give the title compound (3.5 g, Y.:62%).

1. concentrationThe solution was concentrated under reduced pressure
2. customprecipitates
3. filtrationwere collected by filtration
4. dissolutionThe precipitates were dissolved in methanol
5. concentrationThe solution was concentrated under reduced pressure
6. customprecipitates
7. filtrationwere collected by filtration
8. washwashed with methanol
9. customdried under reduced pressure