Ammonia → 2-(4-Nitrophenylamino)ethanesulfonamide

HRID 1393833Notes

Reaction equation

HRID 1393833 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][S:13](Cl)(=[O:15])=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2].[NH3:17]>>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][S:13]([NH2:17])(=[O:15])=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 585866722-[(4-Nitrophenyl)amino]ethanesulfonyl chloride

Product 1

HCID 231044412-(4-Nitrophenylamino)ethanesulfonamide

Procedure

2-[(4-Nitrophenyl)amino]ethanesulfonyl chloride (9) (0.5 g) was mixed with 4 mL of aqueous ammonia (22%) at room temperature. The mixture was left for 1 hour and the precipitate that formed was then filtered off by suction and reslurried in water. The crude product was recrystallized from ethanol to give 0.23 g of expected product with a melting point of 170° C. The results of the elemental analysis were as follows:

Workup

  1. customthe precipitate that formed
  2. filtrationwas then filtered off by suction
  3. customThe crude product was recrystallized from ethanol

Sources & evidence

ORD record
ord-07bd401065fb4d39a4169e056ee297d3
Source dataset
uspto-grants-2008_03
Patent number
US07347879B2

Reaction notes

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