Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69203144, compound

HRID 1393840Notes

Reaction equation

HRID 1393840 reaction equation
[CH3:1][O:2][C:3](=[O:19])[CH:4]([NH:9][C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=1)[CH2:5][CH2:6][S:7][CH3:8].C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:32].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:32].[ClH:32].[CH3:1][O:2][C:3](=[O:19])[CH:4]([NH:9][C:10]1[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=1)[CH2:5][CH2:6][S:7][CH3:8]

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 69203944HCID 69203944, compound

Product 1

HCID 69203144HCID 69203144, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 4-methylsulfanyl-2-(4-nitrophenylamino)butyric acid methyl ester (28) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-38f28a99101d468b85cbac2249707425
Source dataset
uspto-grants-2008_03
Patent number
US07347879B2

Reaction notes

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