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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1393876Generated: October 25, 2026

Methanol → Methyl 2-(3,4-dihydroxyphenyl)-2-hydroxyacetate

https://huagongshe.com/reaction/1393876

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSulfuric AcidHCID 1118—
Reactant(+-)-3,4-Dihydroxymandelic acidHCID 85782—
ProductMethyl 2-(3,4-dihydroxyphenyl)-2-hydroxyacetateHCID 22938264—

Reaction Steps

3,4-Dihydroxymandelic acid is refluxed in methanol in the presence of sulfuric acid, to give methyl 2-(3,4-dihydroxyphenyl)-2-hydroxyacetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07348017B2
Source datasetuspto-grants-2008_03
ORD IDord-238d78a48ef2436da1a5e1ed1460101d
Source noteuspto-grants-2008_03