Methanol → Methyl 2-(4-nitrophenyl)propionate

HRID 1393877Notes

Reaction equation

[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]([CH3:14])[C:11]([OH:13])=[O:12])=[CH:6][CH:5]=1)([O-:3])=[O:2].S(=O)(=O)(O)O.[CH3:20]O>>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([CH:10]([CH3:14])[C:11]([O:13][CH3:20])=[O:12])=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

Reactant 3

HCID 887Methanol

HCID 1118Sulfuric Acid

HCID 892442-(4-Nitrophenyl)propionic acid

Product 1

HCID 3016521Methyl 2-(4-nitrophenyl)propionate

Procedure

2-(4-Nitrophenyl)propionic acid is refluxed in methanol in the presence of sulfuric acid, to give methyl 2-(4-nitrophenyl)propanoate.

Sources & evidence

ORD record: ord-c3fac0c078094da9808f5cd4fc2529ec
Source dataset: uspto-grants-2008_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07348017B2

Reaction notes

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