Methanol → HCID 22938283, compound

HRID 1393878Notes

Reaction equation

HRID 1393878 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([OH:8])[C:5]([O:9][CH3:10])=[CH:4][C:3]=1[CH2:11][C:12]([OH:14])=[O:13].S(=O)(=O)(O)O.[CH3:20]O>>[Br:1][C:2]1[CH:7]=[C:6]([OH:8])[C:5]([O:9][CH3:10])=[CH:4][C:3]=1[CH2:11][C:12]([O:14][CH3:20])=[O:13]

Participants

4

Reactant 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 612497HCID 612497, compound

Product 1

HCID 22938283HCID 22938283, compound

Procedure

2-Bromo-4-hydroxy-5-methoxyphenylacetic acid is refluxed in methanol in the presence of sulfuric acid, to give methyl 2-(2-bromo-4-hydroxy-5-methoxyphenyl)acetate.

Sources & evidence

ORD record
ord-05cfd2ea5a6448a4a8435da929e32d19
Source dataset
uspto-grants-2008_03
Patent number
US07348017B2

Reaction notes

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