HCID 86599747, compound → HCID 86599746, compound

HRID 1393915Notes

Reaction equation

HRID 1393915 reaction equation
C(OC([NH:11][C@H:12]1[CH2:17][CH2:16][CH2:15][N:14]([P:18]([NH:23][CH2:24][CH3:25])([NH:20][CH2:21][CH3:22])=[O:19])[C:13]1=[O:26])=O)C1C=CC=CC=1>CO.[Pd]>[NH2:11][C@H:12]1[CH2:17][CH2:16][CH2:15][N:14]([P:18]([NH:23][CH2:24][CH3:25])([NH:20][CH2:21][CH3:22])=[O:19])[C:13]1=[O:26]

Participants

4

Reactant 1

HCID 86599747HCID 86599747, compound

Product 1

HCID 86599746HCID 86599746, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Palladium black (60 mg) was added to a solution of (3S)-3-benzyloxycarbonylamino-1-bis(ethylamino)phosphinyl-2-piperidone (600.3 mg, 1.5698 mmol) in methanol (6 mL), and the resulting mixture was stirred at room temperature for 3 hours under a hydrogen atmosphere.

Sources & evidence

ORD record
ord-b9bf8940b0624a469da09dd5fc55e732
Source dataset
uspto-grants-2008_03
Patent number
US07348318B2

Reaction notes

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