HCID 178514256, compound → HCID 178514262, compound

HRID 1393925Notes

Reaction equation

HRID 1393925 reaction equation
C(OC([NH:11][C:12]1([PH:20]([NH:22][C:23](=[O:30])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:21])[CH2:17][CH2:16][CH2:15][N:14]([NH2:18])[C:13]1=[O:19])=O)C1C=CC=CC=1>C(O)C.[Pd]>[NH2:11][C:12]1([PH:20]([NH:22][C:23](=[O:30])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:21])[CH2:17][CH2:16][CH2:15][N:14]([NH2:18])[C:13]1=[O:19]

Participants

4

Reactant 1

HCID 178514256HCID 178514256, compound

Product 1

HCID 178514262HCID 178514262, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Palladium black (12.1 mg) was added to a solution of (3S, P (RS))-3-benzyloxycarbonylamino-1-amino(benzoylamino)phosphinyl-2-piperidone (60.5 mg, 0.14 mmol) in ethanol (10 mL), and the resulting mixture was stirred at room temperature for 24 hours under a hydrogen atmosphere.

Sources & evidence

ORD record
ord-b928ca445c7a49ce8c42184055f0e62a
Source dataset
uspto-grants-2008_03
Patent number
US07348318B2

Reaction notes

Loading…