(+-)-1-Aminoindan → HCID 178487239, compound

HRID 1393955Notes

Reaction equation

HRID 1393955 reaction equation
[NH2:1][CH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[CH3:11][O:12][C:13]1[CH:14]=[C:15]2[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=S)[NH:17][CH2:16]2>>[CH:2]1([NH:1][C:18]2[NH:17][CH2:16][C:15]3[C:20](=[CH:21][CH:22]=[C:13]([O:12][CH3:11])[CH:14]=3)[N:19]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 123445(+-)-1-AminoindanHCID 12988848HCID 12988848, compound2×

Product 1

HCID 178487239HCID 178487239, compound

Procedure

The title compound (MS: m/e=294.2 [M+H+]) was prepared in analogy to example 1(b) from (+/−)-1-aminoindan and 6-methoxy-3,4-dihydro-1H-quinazoline-2-thione. 6-Methoxy-3,4-dihydro-1H-quinazoline-2-thione can be prepared by the method of Manetsch, Roman; Zheng, Lei; Reymond, Martine T.; Woggon, Wolf-Dietrich; Reymond, Jean-Louis Chemistry—A European Journal 2004, 10(10), 2487-2506.

Sources & evidence

ORD record
ord-e11d308a6b604fdb862b8ec122b90169
Source dataset
uspto-grants-2008_03
Patent number
US07348332B2

Reaction notes

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