反应详情

A solution of 4,4,4-trifluoro-(4-methylsulfanylphenyl)-butane-1,3-dione (3.0 g) and phenyl hydrazine hydrochloride (1.18 g) in ethanol (20 mL) was refluxed for 7 h. The solvent was evaporated and the residue was chromatographed over silicagel using 20% ethyl acetate in petroleum ether as eluent yielding 2.25 g (% yield=83, Mol. Weight=334) of product as a gum.

1. customThe solvent was evaporated
2. customthe residue was chromatographed over silicagel
3. customyielding 2.25 g (% yield=83, Mol. Weight=334) of product as a gum